Plus, check out Billboard's New Music Latin weekly playlist below!
"All I've done in life is to follow my heart and my passion, and that is Mexican music."
In a blast from the past, the Spaniard performs "Bulería" and "Ave María" alongside Olga Tañón and Ángela Aguilar.
The reggaeton stars sang their new track for the first time on television.
Before kicking off the live broadcast, stars such as Becky G, Anuel AA, David Bisbal, Chiquis and Pepe Aguilar walked the red carpet.
The top nominees of the night are Karol G, Bad Bunny, Daddy Yankee and Becky G.
Spanish-language acts delivered epic sets at the festival during weekend one.
The couple sang two songs off RR, their joint EP released in March.
Peso Pluma and Natti Natasha joined Becky as her surprise guests during her Friday set.
The Puerto Rican hitmaker also delivered a lengthy heartfelt speech, in which he said, "don't believe everything you hear."