The pledge follows up on last year's $15 million donation.
The rapper threw the pigskin around with some youths who signed honorary one-day contracts with team.
Red Hot's founder and its communications director reflect on what has and hasn't changed since the nonprofit's Fela Kuti tribute album came out.
The annual fundraiser launches Nov. 29 and will feature yoga, ice skating, music and more.
The 49-track set boasts music from Pearl Jam, Death Cab for Cutie, Fleet Foxes and more.
"It’s nice to do something to support a great organization like Children’s Hospital; it’s even better when Justin Timberlake is singing at it," Jimmy Kimmel jokes at the event, which raised $5.5M.