The fires have burned more than 40,000 acres since they began last week.
A donation link has been set up to help him and his family.
The latest effort to help those in need depicts Ghostface from the "Scream" movies dressed as a California firefighter.
The rocker's wife revealed that are safe after losing their Malibu home over the weekend.
Singer Les Claypool posted images of the destroyed house, writing "my heart hurts for him and his family."
The donation is earmarked for those in Altadena and Pasadena who have lost homes, as well as to churches and community centers.
Ticket information and performers for the Jan. 30 event will be announced in the coming days.
The Smashing Pumpkins leader praised the heroic work of fire crews battling the most destructive fires in the city's history.
The singer also defended ex Elon Musk from a commenter who called him a "climate denier."
Mayer calls photos of his father "the most valuable thing I own," acknowledging that countless memories went up in flames over the last three days.
