Grohl famously portrayed Satan in the “Tribute” music video and the 2006 film Tenacious D in The Pick of Destiny.
Kieran Culkin and Jennifer Coolidge were also scheduled to host the iconic sketch comedy series.
The Chicks, HAIM, The War On Drugs, Father John Misty, Japanese Breakfast, Suki Waterhouse are also among artists set to take the stage at the jam-packed festival.
The Dave Grohl-fronted band is embarking on a North American tour later this spring.
This year’s Bonnaroo lineup just dropped and it’s looking pretty, pretty nice. Among the EDM acts, Zeds Dead and Liquid Stranger headline Thursday night, typically the “soft open” for the main festival weekend though no less important. GRiZ, Subtronics, Peekaboo, Apashe, Boogie T b2b Dirt
Plus: Grateful Dead, Berner, Baby Keem, Polyphia, Foo Fighters and Demon Hunter debut in Top Album Sales’ top 10.