Gracie Abrams, G Flip, Moore Kismet and Paul Klein from LANY will be this year's guest artists.
The event will also honor U.S. Senate Majority Leader Chuck Schumer (D-N.Y.) and Sen. Bill Cassidy (R-La.).
All education programs are free for students with registration.
Fans of The Boss will find plenty to love in the Los Angeles exhibit that runs through April 2023.
Shawn Mendes and Rosalía are the other co-chairs of the fund-raising drive, which aims to raise $3 million to $5 million.