Her black-and-white gown was designed by Thom Browne.
"I'm representing the House of Chanel and Karl at the same time," Cardi said of her outfits.
The custom Jacquemus tweed suit was paired with a floral cape.
The look matched perfectly with this year's theme, Karl Lagerfeld: A Line of Beauty.
The actor came dressed as Karl Lagerfeld's cat, Choupette.
She paired the look with her hair in a long black braid.
Doja channeled Choupette with a prosthetic nose and a cat ear headpiece.
This is Anitta's third time attending the event.
The singer serves as one of this year's co-chairs.
Leto will also produce the film, which comes with the full support of the Karl Lagerfeld fashion house.