The Mexican-American band performed their Billboard chart-topping hit.
"To be an agent of change you just have to differentiate what is right from what is wrong," said the Colombian superstar.
Genre staples Pavel Núñez, Fernando Villalona, La Materialista, Jandy Ventura and Ilegales came together at the 20th anniversary of the awards ceremony.
"Me gusta andar con la plebada, puras fresitas operadas," JOP sang at the 20th anniversary of the award ceremony.
Angel & Khriz, R.K.M & Ken-Y, Alexis & Fido, Zion & Lennox and more make a statement as the bold powerhouse duos of reggaetón.
