"I really thought I was going to be a one-hit wonder," he tells Billboard, sharing how he overcame depression to keep creating.
Featured artist 21 Savage, meanwhile, posts his third champ on the radio chart.
The two rappers' team-up also opens at No. 9 on the Hot 100.
Ye was taken to task by the family for privately supporting them, but then doing something to "publicly... set us all back."
The superstar is looking to trademark the flute for NFTs, toys, clothing, virtual environments and more.
The "Crush on You" rapper also lovingly explained that Cardi is like a "little sister" to her.
"This is exactly what the goal was: working together [for him to be] this person that would inspire athletes and kids, using music as a vehicle to do that."
A few comments on his Instagram post suggested stars like Michael B. Jordan, Denzel Washington or even Kanye himself should play him in a movie.
The duo's new album as Unc & Phew arrives Friday (Oct. 7).
Diddy also called the former Bad Boy Records artist a "fake pastor."