The label's first signee, Moskino, is set to release his King of the Underdogs project on June 6.
Merlin will provide Nina with music, API-backed operational infrastructure, and support and mentorship, including collaboration with Merlin members.
The app will provide "deeper insights into careers and fan bases."
The San Francisco-based label will release a collaborative project from N3ON and his network of creatives.
Create plans to invest an additional $50 million into the label over the next two years.
"Together they form a potent team to help the incredible artists on our label reach their full creative potential and drive our ongoing transformation," says CMG chief Tom March.
The singer/songwriter will play stadiums this summer.
The deal also reunites the three-time Grammy winner with MCA Nashville for her music catalog.
One report puts the purchase price for the minority stake at $200 million.
The "Merry Go 'Round" singer-songwriter was the last artist signed to Lost Highway back in 2011, before it was absorbed by Mercury Nashville.