Plus, Elton John and Brandi Carlile will make their debut as a duo on the show.
The pop superstar, who took on the roles of both host and musical guest, also performed tracks from her new album, Mayhem.
The pop superstar took on double duty as both host and musical guest during the March 8 episode.
Both songs are featured on her third album, So Close to What.
Tate McRae is also locked in to perform a week prior.
The former Beatle closed out the three-hour event with a historic nod to one of the most celebrated albums in rock history.
The four-season Saturday Night Live castmember paid tribute to his late castmates Chris Farley, Phil Hartman & more.
O'Connor famously tore up a photo of then-Pope John Paul II to end her 1992 Saturday Night Live performance.
"I can't believe what I'm watching," the British singer wrote.
